World Neuron Congress November 26-27, 2018 Helsinki, Finland

Shlomi Hanassy is the owner and establisher of Hanassy R&D Ltd. IL. Shlomi is an algorithm developer and neurobiologist specialized in motor control and vision processing. He is also an inventor and experienced developer of several innovations in those fields. In 2011-2012 he worked as algorithm developer at Wellsens tech (http://www.wellsense-tech.com/), developing algorithms for pressure mat while serving as a consultant for the EU “Stiff-flop” project (http://www.stiff-flop.eu/). During 2007-2010 he was a PhD student and algorithm developer of visual substitution devises at Amir Amedi’s lab for higher brain functions while serving as a coworker in Benny Hochner’s lab for motor control and at the EU “Octopus project”(http://www.octopusproject.eu/). Since 2007 Shlomi is holding an M.sc in medical neurobiology from the Hebrew University (Hadassah Ein Carem medical school) and a B.A in computer science and administration from the Open University of

Israel (since 2003).

A novel biologically inspired theory for brain information processing and encoding is presented for the first time. In this model, the world is described as networks of stabilizers components which claimed to control all biological structures, embedded in and implemented by organic systems of any form. Significant evidence for the theory is first presented in a review, and then the theory is described in an abstract way and how it is connected to information theory and qualia. And finally, preliminary results of using a simulation of the model as unsupervised ML system to solve a task are presented with comparison to classical deep learning algorithms.

Mohammad Ghadirivasfi was graduated in psychiatry from Iran University of Medical Sciences (IUMS), Iran. He was the head of Iran Mental Hospital for 13 years and achieved years of experience in research, teaching and administration in hospital and during this period, his effort was highly effective to establish Iranian DNA Bank for Genetic and Epigenetic Studies in Psychiatric Disorders. He is interested in improving education of medical student and residency in psychiatry. He has academic publications and is one of the authors of the Iranian curriculum of general psychiatry, addiction and risky behavior fellowship and the sleep textbook (in Persian) sponsored by IUMS (Iran University of Medical Sciences). He was the secretary of 5th Basic and clinical Neuroscience Congress in 2016 Tehran, Iran. Currently, he is the head of neurocognitive center in Iran Mental Hospital.

Addiction is a chronic, relapsing disorder in which addict people mostly go through sustained habit‐based drug use and periods of abstinent. It is supposed to externalizing psychopathologies including disruptive disorders and antisocial personality disorder precedes or co-occurs with substance use disorder in at least noticeable percentage of them. Interestingly, all externalizing psychopathologies are observed from adolescence which is accompanied by risky behaviors like substance use. It is believed that three fundamental structure of neurocognitive function in children which are impaired, make them predispose to take risky behaviors and drug use. Impulsivity, decision making and working memory impairment taken together, play the main role in future brain’s reward neurocircuitry changes. Under limited inhibitory control in one hand and an overactive reward system on other hand, prone adolescences try and sustain using substance. Due to repeated intense drug rewards and neuroplasticity occurred in reward system, a compensatory anti-reward process reduces pleasurable feeling and at neuroanatomical view, a neurocircuitry migration from ventral to dorsal striatum happens. Disregarding its adverse effects and consequences, a significant percentage of addict people keep using substance. It is suggested to screen risky behavior characteristics in childhood and early adolescent in order to detect and invest on pharmacological and neurocognitive rehabilitation as a preventive program. Considering this sort of intervention from early life, it is supposed that reward system should keep unchanged until early adulthood which inhibitory system develops.

Mihai Stelian Moreanu is currently one of the top medical students at Carol Davila University of Medicine and Pharmacy. His interests lie in neurological implications

of diseases and neurosurgery, having already completed his medical summer stage at Bagdasar-Arseni Clinical Emergency Hospital, the best neurosurgical public

center in Bucharest. His medical background includes the participation to numerous national and international congresses in Romania (IMSCB, ZEM, MEDICS) and

also abroad (FEBS 2018) gaining a vast understanding of the mechanisms of brain functioning. Also, during his medical practice he assisted to numerous surgeries

and participated to Romanian Student Surgical Society activities getting hands-on experience during surgical workshops.

 

Meningiomas are benign extra-axial tumors, originating from the meningeal arachnoidal cells, making up 20% of the intracranial

primary tumors. Surgical management of meningiomas is one of the most challenging procedures posing a high risk of affecting

the critical neurovascular centers of the brain. This paper attempts to identify the way Para clinical brain investigations coupled with a

well-established surgical procedure lead to an efficient and strategic treatment of meningioma, starting with a real case of a 50-year-old

woman. The clinical background of the patient was represented by frontal headaches, rare epileptic crisis, sudden dizziness, blurry vision,

loss of equilibrium and exhaustion. The Para clinical investigation included contrast MRI showing a homogenous irregular expanding

tumor process in the frontal-orbital left space. Localization, depth, diameters were also shown on MRI. Moreover, Digital Angiography

was used to identify the source of vascularization, highlighting a slight displacement of the arterial irrigation of Willis Polygon towards

the tumoral process. These symptoms and investigations led to diagnosing a sphenoid left wing meningioma. The treatment was mainly

focused on the neurosurgical intervention, having several purposes: rejecting the meningioma, establishing the anatomo pathological

diagnosis, developing the therapeutic plan. The surgical procedure included the following steps: positioning, incision, craniotomy,

tumor exposure, devascularization, decompression, extra capsular dissection, tumor removal, closure. The surgical approach was on

the frontotemporal side and after a step-by-step incision, the tumor was exposed. The excision strategy was focused on fragmentation

and mild dissection of the surrounding brain tissue. Also, while the tumor surface coagulated constantly, it lost volume and allowed an

easy dissection. The final result was favorable – the patient regained her balance. Getting a better understanding of the neurosurgical

steps of treating meningiomas will lead to finding strategies that will improve the patient's treatment and his quality of life.